SCHEMBL7074510

SCHEMBL7074510

CN(C)c1cccc(Oc2cc(C#N)cc(C#N)c2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 2/20 0.41
RAB9A P51151 2/20 0.40
F2 P00734 1/20 0.39
F10 P00742 1/20 0.39
ALDH1A1 P00352 3/20 0.38
MAPT P10636 2/20 0.38
AR P10275 2/20 0.38
BCHE P06276 1/20 0.38
ACHE P22303 1/20 0.38
NPC1 O15118 1/20 0.38
MAPK1 P28482 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
MEN1 O00255 1/20 0.38
MITF O75030 1/20 0.38
GAA P10253 1/20 0.38
GFER P55789 1/20 0.38
KMT2A Q03164 1/20 0.38
NLRP1 Q9C000 1/20 0.38
NOD2 Q9HC29 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7070749 0.84 SMN1; SMN2 (0.50) RAB9AALDH1A1MAPTARNPC1
SCHEMBL30085363 0.82 ALDH1A1 (0.52) APPF2F10ALDH1A1MAPT
SCHEMBL390876 0.82 ALDH1A1 (0.52) APPF2F10ALDH1A1MAPT
SCHEMBL7072557 0.81 PDE4A (0.50) ALDH1A1MAPTARSMN1; SMN2MEN1
SCHEMBL7069974 0.81 PDE4A (0.50) ALDH1A1MAPTARSMN1; SMN2MEN1
SCHEMBL4195434 0.79 CYP19A1 (0.54) APPF2F10ALDH1A1AR
SCHEMBL7070717 0.79 MEN1 (0.50) RAB9AALDH1A1MAPTNPC1SMN1; SMN2
SCHEMBL26666746 0.79 ALDH1A1 (0.51) APPRAB9AF2F10ALDH1A1
SCHEMBL8551347 0.78 SLC6A4 (0.45) RAB9AALDH1A1MAPTARMAPK1
SCHEMBL7071827 0.78 AR (0.59) ALDH1A1MAPTARACHESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030181334-A1 Herbicidal method BAYER CROPSCIENCE LIMITED (GB) 2003-09-25 US disclosed
WO-2003051119-A1 NEW HERBICIDAL COMPOUNDS AND METHOD BAYER CROPSCIENCE LIMITED (GB) 2003-06-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030181334-A1 Herbicidal method DDT, HAAO, CYP4X1 APP 4176/4885RAB9A 3566/4885F2 4287/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.