Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 16/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.36 |
| ▸ | ESR1 | P03372 | 14/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7072760 | 0.87 | OPRM1 (0.33) | ESR2OPRM1OPRD1OPRK1ESR1 | |
| SCHEMBL6799265 | 0.76 | ESR2 (0.43) | ESR2OPRM1OPRD1OPRK1ESR1 | |
| SCHEMBL6793852 | 0.63 | ESR2 (0.38) | ESR2OPRM1OPRD1OPRK1ESR1 | |
| SCHEMBL26135697 | 0.62 | TYR (0.42) | ESR2OPRM1OPRD1OPRK1ESR1 | |
| SCHEMBL10899063 | 0.59 | CNR2 (0.46) | ESR2OPRM1OPRD1OPRK1ESR1 | |
| SCHEMBL9355063 | 0.59 | ESR2 (0.47) | ESR2ESR1 | |
| SCHEMBL28930025 | 0.57 | PDK2 (0.46) | ESR2ESR1 | |
| SCHEMBL28852732 | 0.56 | TP53 (0.45) | ESR2OPRM1OPRD1OPRK1ESR1 | |
| SCHEMBL29272574 | 0.56 | TP53 (0.45) | ESR2OPRM1OPRD1OPRK1ESR1 | |
| SCHEMBL9343209 | 0.56 | ESR2 (0.57) | ESR2ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339662-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS III | KARO BIO AB (SE) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002046134-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS III | KARO BIO AB (SE) | 2002-06-13 | — | — | WO | disclosed |