Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 5/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074686 | 0.87 | ESR2 (0.38) | OPRM1OPRD1OPRK1ESR1ESR2 | |
| SCHEMBL6793852 | 0.73 | ESR2 (0.38) | OPRM1OPRD1OPRK1NR3C1ESR1 | |
| SCHEMBL6793856 | 0.66 | NR3C1 (0.34) | NR3C1ESR1ESR2 | |
| SCHEMBL6799265 | 0.63 | ESR2 (0.43) | OPRM1OPRD1OPRK1ESR1ESR2 | |
| Hydrochloric Acid SCHEMBL2390199 | 0.59 | OPRM1 (0.42) | OPRM1OPRD1OPRK1 | |
| SCHEMBL7212874 | 0.57 | OPRM1 (0.42) | OPRM1OPRD1OPRK1ESR1ESR2 | |
| SCHEMBL13899941 | 0.57 | ESR1 (0.54) | OPRM1OPRD1OPRK1ESR1ESR2 | |
| SCHEMBL14158763 | 0.57 | ESR2 (0.41) | OPRM1OPRD1OPRK1ESR1ESR2 | |
| SCHEMBL26135919 | 0.56 | MEN1 (0.42) | OPRM1OPRD1OPRK1ESR1ESR2 | |
| SCHEMBL6940455 | 0.55 | ESR2 (0.44) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339662-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS III | KARO BIO AB (SE) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002046134-A1 | NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS III | KARO BIO AB (SE) | 2002-06-13 | — | — | WO | disclosed |