Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.61 |
| ▸ | F10 | P00742 | 1/20 | 0.56 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | GPR183 | P32249 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28743975 | 0.97 | LMNA (0.58) | LMNASMN1; SMN2F10SPHK1SPHK2 | |
| SCHEMBL7074251 | 0.97 | LMNA (0.66) | LMNASMN1; SMN2F10SPHK1SPHK2 | |
| Acetic Acid SCHEMBL28746408 | 0.94 | LMNA (0.62) | LMNASMN1; SMN2F10FAAHMGLL | |
| SCHEMBL7071611 | 0.92 | F10 (0.59) | LMNASMN1; SMN2F10MAPTMAPK1 | |
| Acetic Acid SCHEMBL27525141 | 0.89 | F10 (0.56) | LMNASMN1; SMN2F10MAPTMAPK1 | |
| SCHEMBL7074608 | 0.88 | F10 (0.61) | LMNASMN1; SMN2F10MAPTMAPK1 | |
| Acetic Acid SCHEMBL27574150 | 0.85 | F10 (0.58) | LMNASMN1; SMN2F10MAPTMAPK1 | |
| SCHEMBL7074110 | 0.82 | LMNA (0.53) | LMNASMN1; SMN2F10L3MBTL1GPR183 | |
| SCHEMBL7076666 | 0.82 | LMNA (0.72) | LMNAF10MAPTMAPK1L3MBTL1 | |
| SCHEMBL7070008 | 0.82 | GAA (0.56) | LMNASMN1; SMN2F10GPR183ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |