Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GPR183 | P32249 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.48 |
| ▸ | PLG | P00747 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27538656 | 0.97 | USP2 (0.51) | LMNASMN1; SMN2USP2L3MBTL1GAA | |
| SCHEMBL7071611 | 0.89 | F10 (0.59) | LMNASMN1; SMN2L3MBTL1ALDH1A1TSHR | |
| Acetic Acid SCHEMBL27525141 | 0.86 | F10 (0.56) | LMNASMN1; SMN2L3MBTL1ALDH1A1TSHR | |
| SCHEMBL7074873 | 0.86 | LMNA (0.48) | LMNASMN1; SMN2ALDH1A1F10KMT2A | |
| SCHEMBL7071911 | 0.84 | L3MBTL1 (0.61) | LMNAUSP2L3MBTL1GAAALDH1A1 | |
| Acetic Acid SCHEMBL27550401 | 0.83 | LMNA (0.46) | LMNASMN1; SMN2ALDH1A1PKMF10 | |
| SCHEMBL7074251 | 0.83 | LMNA (0.66) | LMNASMN1; SMN2L3MBTL1ALDH1A1TSHR | |
| SCHEMBL7075851 | 0.83 | USP2 (0.61) | LMNASMN1; SMN2USP2L3MBTL1GAA | |
| Acetic Acid SCHEMBL27550437 | 0.82 | L3MBTL1 (0.57) | LMNAUSP2L3MBTL1GAAALDH1A1 | |
| SCHEMBL7074761 | 0.82 | LMNA (0.61) | LMNASMN1; SMN2L3MBTL1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |