SCHEMBL7074829

SCHEMBL7074829

CC(C)C(N)C(=O)c1nnc(C(C)(C)c2ccccc2)o1

nearest known ligand 0.49

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ELANE P08246 14/20 0.49
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
APLNR P35414 1/20 0.34
KIF11 P52732 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7075284 0.99 ELANE (0.48) ELANECYP1A2CYP2D6MAPTKMT2A
SCHEMBL7956686 0.82 ELANE (0.48) ELANECYP1A2CYP2D6MAPTKMT2A
SCHEMBL6804849 0.80 ELANE (0.39) ELANE
SCHEMBL27158525 0.80 PTPN1 (0.46) ELANEMAPTKMT2AAPLNR
Hydrochloric Acid SCHEMBL6806816 0.79 ELANE (0.39) ELANE
Hydrochloric Acid SCHEMBL7129582 0.79 ELANE (0.39) ELANE
Hydrochloric Acid SCHEMBL7125040 0.78 ELANE (0.51) ELANEMAPTKMT2AKIF11
SCHEMBL7071124 0.77 ELANE (0.54) ELANEMAPT
Hydrochloric Acid SCHEMBL7125586 0.74 PTPN1 (0.55) ELANEMAPTKMT2A
Hydrochloric Acid SCHEMBL7125581 0.74 PTPN1 (0.55) ELANEMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030153758-A1 1,3,4-Oxadiazole derivatives and process for producing the same ONO PHARMACEUTICAL CO., LTD. 2003-08-14 US claimed
US-6534658-B1 Intermediates for producing pharmaceuticals ONO PHARMACEUTICAL CO., LTD. (JP) 2003-03-18 US claimed
EP-1162199-A1 1,3,4-OXADIAZOLE DERIVATIVES AND PROCESS FOR PRODUCING THE SAME ONO PHARMACEUTICAL CO., LTD. (JP) 2001-12-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030153758-A1 1,3,4-Oxadiazole derivatives and process for producing the same OXA1L, CYP1B1, OXER1 ELANE 4189/4885CYP1A2 8/4885CYP2D6 21/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.