Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | GRM6 | O15303 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TPMT | P51580 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232764 | 0.87 | SLC7A5 (0.40) | KDM4EGRM6KMT2AMEN1TDP1 | |
| SCHEMBL1767847 | 0.87 | KDM4E (0.40) | KDM4EGRM6CYP2C9CYP2C19KMT2A | |
| SCHEMBL7075526 | 0.85 | KEAP1 (0.42) | KDM4EGRM6KMT2AMEN1TDP1 | |
| SCHEMBL7078434 | 0.85 | HSD17B10 (0.42) | KDM4EGRM6KMT2AMEN1TDP1 | |
| SCHEMBL7071957 | 0.85 | CYP3A4 (0.46) | KDM4ENPSR1KMT2AMEN1ALDH1A1 | |
| SCHEMBL12276981 | 0.85 | KDM4E (0.58) | KDM4EGRM6CYP2C9CYP2C19NPSR1 | |
| SCHEMBL11881146 | 0.82 | KDM4E (0.79) | KDM4ECSNK2A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL27996077 | 0.79 | CA12 (0.42) | KDM4EGRM6GABRA1GABRG2GABRB3 | |
| SCHEMBL16114294 | 0.79 | GRM6 (0.40) | KDM4EGRM6CYP2C9CYP2C19NPSR1 | |
| SCHEMBL29594182 | 0.79 | KDM4E (0.39) | KDM4EGRM6CYP2C9CYP2C19NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003052053-A2 | NUCLEOSIDE LIBRARIES AND COMPOUNDS BY MCC COMBINATORIAL STRATEGIES ON SOLID SUPPORT | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |