Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.40 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | GRM6 | O15303 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6232764 | 0.85 | SLC7A5 (0.40) | HSD17B10KDM4EGRM6CA12CA1 | |
| SCHEMBL1767847 | 0.85 | KDM4E (0.40) | HSD17B10KDM4EGRM6CA12CA1 | |
| SCHEMBL7074918 | 0.85 | KDM4E (0.56) | KDM4EGRM6CA12CA1CA2 | |
| SCHEMBL7075526 | 0.84 | KEAP1 (0.42) | HSD17B10KDM4EGRM6CA12CA1 | |
| SCHEMBL7324883 | 0.84 | LCK (0.39) | HSD17B10KDM4ELCKGRM6CA12 | |
| SCHEMBL7071957 | 0.84 | CYP3A4 (0.46) | HSD17B10KDM4EGLAAKR1C3AKR1C2 | |
| SCHEMBL28992396 | 0.81 | KDM4E (0.44) | HSD17B10KDM4EGLAAKR1C3AKR1C2 | |
| SCHEMBL15920614 | 0.79 | KDM4E (0.47) | HSD17B10KDM4EGLAMYCNR4A1 | |
| SCHEMBL4628585 | 0.79 | KDM4E (0.47) | HSD17B10KDM4EGLAMYCNR4A1 | |
| SCHEMBL27996077 | 0.78 | CA12 (0.42) | HSD17B10KDM4EGLAGRM6CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003052053-A2 | NUCLEOSIDE LIBRARIES AND COMPOUNDS BY MCC COMBINATORIAL STRATEGIES ON SOLID SUPPORT | RIBAPHARM INC. (US) | 2003-06-26 | — | — | WO | disclosed |