Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 7/20 | 0.48 |
| ▸ | FPR2 | P25090 | 6/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL27550415 | 0.97 | PROKR1 (0.46) | PROKR1FPR2F10MAPTTHRB | |
| SCHEMBL7074432 | 0.80 | HDAC4 (0.47) | PROKR1FPR2MAPTTHRBALDH1A1 | |
| SCHEMBL7070540 | 0.78 | TSHR (0.54) | F10MAPTALDH1A1NPSR1LMNA | |
| SCHEMBL7071435 | 0.78 | KMT2A (0.64) | F10MAPTALDH1A1NPSR1LMNA | |
| Acetic Acid SCHEMBL27525156 | 0.76 | HTT (0.52) | F10MAPTALDH1A1NPSR1LMNA | |
| SCHEMBL7077254 | 0.76 | F10 (0.66) | F10MAPTALDH1A1LMNAGAA | |
| SCHEMBL7071636 | 0.75 | F10 (0.53) | F10ALDH1A1LMNAPOLBMEN1 | |
| SCHEMBL7077553 | 0.75 | F10 (0.65) | F10MAPTLMNAPOLBMEN1 | |
| SCHEMBL7076666 | 0.75 | LMNA (0.72) | F10MAPTALDH1A1LMNAGAA | |
| SCHEMBL7070621 | 0.74 | MEN1 (0.55) | F10MAPTALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |