Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 9/20 | 0.51 |
| ▸ | IMPDH2 | P12268 | 12/20 | 0.49 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7077282 | 0.88 | IMPDH2 (0.52) | AAK1IMPDH2IMPDH1 | |
| SCHEMBL7075192 | 0.88 | IMPDH2 (0.54) | AAK1IMPDH2IMPDH1 | |
| SCHEMBL7080323 | 0.88 | IMPDH2 (0.53) | AAK1IMPDH2 | |
| SCHEMBL7079510 | 0.88 | AAK1 (0.52) | AAK1IMPDH2IMPDH1 | |
| SCHEMBL7075708 | 0.84 | AAK1 (0.52) | AAK1IMPDH2IMPDH1 | |
| SCHEMBL7075706 | 0.84 | IMPDH2 (0.55) | AAK1IMPDH2IMPDH1 | |
| SCHEMBL7078966 | 0.83 | GPR119 (0.53) | AAK1IMPDH2IMPDH1 | |
| SCHEMBL7132866 | 0.82 | IMPDH2 (0.50) | AAK1IMPDH2IMPDH1 | |
| SCHEMBL7078390 | 0.82 | IMPDH2 (0.51) | AAK1IMPDH2IMPDH1 | |
| SCHEMBL7078381 | 0.79 | IMPDH2 (0.51) | AAK1IMPDH2IMPDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105073-A1 | Quinolone derivatives | CELLTECH R&D LIMITED (GB) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105073-A1 | Quinolone derivatives | IFNAR1, CBR1, IMPDH1 | AAK1 4571/4885IMPDH2 8/4885IMPDH1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.