Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 3/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491990 | 0.82 | TSHR (0.63) | TSHRSRCCETPCA12CA1 | |
| SCHEMBL27780073 | 0.80 | TSHR (0.61) | TSHRSRCCETPCA12CA1 | |
| SCHEMBL8412635 | 0.78 | TSHR (0.66) | TSHRSRCCETPFOLH1PDPK1 | |
| SCHEMBL7079628 | 0.77 | SRC (0.44) | SRCCA12CA1CA2KDM4E | |
| SCHEMBL3067248 | 0.75 | TSHR (0.55) | TSHRSRCCETPCA12CA1 | |
| SCHEMBL3077577 | 0.75 | TSHR (0.59) | TSHRSRCCETPCA12CA1 | |
| SCHEMBL8412292 | 0.74 | TSHR (0.50) | TSHRSRCCETPKMT2ANR4A1 | |
| SCHEMBL3068400 | 0.74 | TSHR (0.63) | TSHRSRCCETPCA12CA1 | |
| SCHEMBL3062985 | 0.74 | — | — | |
| SCHEMBL1604320 | 0.74 | TSHR (0.53) | TSHRSRCCETPCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003060191-A2 | NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT | UNIVERSITY OF DAYTON (US) | 2003-07-24 | — | — | WO | disclosed |