Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA | P35790 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.44 |
| ▸ | CHKB | Q9Y259 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7071417 | 1.00 | CHKA (0.53) | CHKAALDH1A1TSHRMAPK1CYP3A4 | |
| SCHEMBL7072445 | 1.00 | CHKA (0.53) | CHKAALDH1A1TSHRMAPK1CYP3A4 | |
| SCHEMBL5741268 | 1.00 | CHKA (0.53) | CHKAALDH1A1TSHRMAPK1CYP3A4 | |
| SCHEMBL7494593 | 0.92 | ALDH1A1 (0.54) | CHKAALDH1A1TSHRMAPK1CYP3A4 | |
| SCHEMBL5539466 | 0.83 | ALDH1A1 (0.58) | CHKAALDH1A1TSHRMAPK1CYP3A4 | |
| SCHEMBL6310153 | 0.83 | ALDH1A1 (0.64) | CHKAALDH1A1TSHRMAPK1CYP3A4 | |
| SCHEMBL23302919 | 0.82 | ESR1 (0.59) | CHKAALDH1A1TSHRMAPK1CYP3A4 | |
| SCHEMBL5741271 | 0.82 | ESR1 (0.59) | CHKAALDH1A1TSHRMAPK1CYP3A4 | |
| SCHEMBL30712275 | 0.82 | ESR1 (0.59) | CHKAALDH1A1TSHRMAPK1CYP3A4 | |
| SCHEMBL23037542 | 0.82 | ESR1 (0.59) | CHKAALDH1A1TSHRMAPK1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003052026-A1 | AN ANTIOXIDANT COMPOSITION | POLYINOVA AB (SE) | 2003-06-26 | — | — | WO | disclosed |