SCHEMBL5741271

SCHEMBL5741271

CCCCCCc1ccc(N(C)C)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.59
ADRA2A P08913 2/20 0.59
ADORA3 P0DMS8 2/20 0.59
TACR2 P21452 2/20 0.59
SLC6A2 P23975 2/20 0.59
SLC6A4 P31645 2/20 0.59
SLC6A3 Q01959 2/20 0.59
ALDH1A1 P00352 2/20 0.59
CYP3A4 P08684 2/20 0.59
KDM4E B2RXH2 1/20 0.59
LMNA P02545 1/20 0.59
SHBG P04278 1/20 0.59
TP53 P04637 1/20 0.59
HSPD1 P10809 1/20 0.59
ADRB3 P13945 1/20 0.59
HTR2C P28335 1/20 0.59
HSPE1 P61604 1/20 0.59
HIF1A Q16665 1/20 0.59
TST Q16762 1/20 0.59
HSD17B10 Q99714 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1451841 1.00 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL30712275 1.00 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL10354229 1.00 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL23037542 1.00 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL29013341 1.00 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL23302919 1.00 ESR1 (0.59) ESR1ADRA2AADORA3TACR2SLC6A2
Hydrochloric Acid SCHEMBL23303513 0.98 ESR1 (0.57) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL20633866 0.98 CHKA (0.56) ESR1ADRA2AADORA3TACR2SLC6A2
SCHEMBL727512 0.91 ALDH1A1 (0.56) ESR1ADRA2AADORA3TACR2SLC6A2
Hydrochloric Acid SCHEMBL2868873 0.89 ALDH1A1 (0.54) ESR1ADRA2AADORA3TACR2SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250107971-A1 POWDER-LIQUID-TYPE DENTAL PLATE LINER TOKUYAMA DENTAL CORPORATION (JP) 2025-04-03 US disclosed
EP-4464302-A1 POWDER-LIQUID-TYPE DENTURE BASE LINER Tokuyama Dental Corporation (JP) 2024-11-20 EP disclosed
US-20240018279-A1 Cyclic Containing Polymer Compositions Obtained Using Transition Metal Bis(Phenolate) Catalyst Complexes and Process for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-01-18 US disclosed
US-20230357454-A1 Methods for Delivery of Non-Aromatic Solutions to Polymerization Reactors EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-11-09 US disclosed
US-20230348640-A1 Propylene Copolymers Obtained Using Transition Metal Bis(Phenolate) Catalyst Complexes and Homogeneous Process for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-11-02 US disclosed
US-20230348642-A1 Ethylene-Alpha-Olefin-Diene Monomer Copolymers Obtained Using Transition Metal Bis(Phenolate) Catalyst Complexes and Homogeneous Process for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-11-02 US disclosed
US-20230348634-A1 Propylene Polymers Obtained Using Transition Metal Bis(Phenolate) Catalyst Complexes and Homogeneous Process for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-11-02 US disclosed
US-20230312772-A1 Multidentate Lewis Base Catalysts and Methods for use Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-10-05 US disclosed
US-11766669-B2 Hexahydrocyclopenta[e]-as-indacen-1-yl and octahydrobenzo[e]-as-indacen-1-yl based catalyst complexes and process for use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-09-26 US disclosed
US-20230287156-A1 Polyethylene Compositions Obtained Using Transition Metal Bis(Phenolate) Catalyst Complexes and Homogeneous Process for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-09-14 US disclosed
WO-2023135930-A1 POWDER-LIQUID-TYPE DENTURE BASE LINER 株式会社トクヤマデンタル 2023-07-20 WO disclosed
US-20230212330-A1 Metallocene Catalysts for Producing Vinyl-Terminated Polyalphaolefins and Methods Associated Therewith EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-07-06 US disclosed
US-11661465-B2 Dimer selective metallocene catalysts, non-aromatic hydrocarbon soluble activators, and processes to produce poly alpha-olefin oligmers therewith EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-05-30 US disclosed
US-20230141606-A1 Alkylation of Transition Metal Coordination Catalyst Complexes EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-05-11 US disclosed
US-20230035898-A1 CYCLODEXTRIN PROTEIN DRUG CONJUGATES REGENERON PHARMACEUTICALS, INC. 2023-02-02 US disclosed
US-11414436-B2 Non-coordinating anion type activators containing cation having large alkyl groups EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-08-16 US disclosed
US-11377502-B2 Anti-MSR1 antibodies and methods of use thereof REGENERON PHARMACEUTICALS, INC. (US) 2022-07-05 US disclosed
EP-1219625-B1 Novel substituted 2-(6-benzyl-5-oxo-3-phenyl-(S3,7S,7AR)- perhydroimidazol (1,5-C) (1,3) thiazol-7YL) compounds COUNCIL SCIENT IND RES (IN) 2006-05-17 EP disclosed
US-6486328-B1 Substituted 2-[-6-benzyl-5-oxo-3-phenyl-(3s,7s, 7aR)-perhydroimidazol[1,5-c][1,3]thiazol-7yl] compounds COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-11-26 US disclosed
EP-1219625-A1 Novel substituted 2-(6-benzyl-5-oxo-3-phenyl-(S3,7S,7AR)- pherhydroimidazol (1,5-C) (1,3) thiazol-7YL) compounds Council of Scientific and Industrial Research (IN) 2002-07-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230141606-A1 Alkylation of Transition Metal Coordination Catalyst Complexes AS3MT, AP1M1, AP3M1 ESR1 3347/4885ADRA2A 3882/4885ADORA3 2987/4885
US-20250107971-A1 POWDER-LIQUID-TYPE DENTAL PLATE LINER HEATR1, HEATR6, ACTR5 ESR1 2998/4885ADRA2A 3288/4885ADORA3 3058/4885
US-11414436-B2 Non-coordinating anion type activators containing cation having large alkyl groups KCNK10, KCNK4, HCN4 ESR1 986/4885ADRA2A 1018/4885ADORA3 665/4885
US-11766669-B2 Hexahydrocyclopenta[e]-as-indacen-1-yl and octahydrobenzo[e]-as-indacen-1-yl based catalyst complexes and process for use thereof MLX, ZYX, TXN ESR1 569/4885ADRA2A 2659/4885ADORA3 2526/4885
US-20230035898-A1 CYCLODEXTRIN PROTEIN DRUG CONJUGATES SDCBP, DDOST, KRTCAP2 ESR1 3513/4885ADRA2A 2992/4885ADORA3 4752/4885
US-11661465-B2 Dimer selective metallocene catalysts, non-aromatic hydrocarbon soluble activators, and processes to produce poly alpha-olefin oligmers therewith NONO, TPR, ZNF787 ESR1 1036/4885ADRA2A 1022/4885ADORA3 1956/4885
US-11377502-B2 Anti-MSR1 antibodies and methods of use thereof CD47, MSR1, LDLR ESR1 1538/4885ADRA2A 2814/4885ADORA3 1750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.