SCHEMBL7076113

SCHEMBL7076113

C[Si](C)(C)[SiH]([Si](C)(C)C)[Zr](Cl)(Cl)(c1cccc2c1Cc1ccccc1-2)C1C=Cc2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2806876 0.88 PNMT (0.32) PNMTNPC1RAB9A
SCHEMBL2801806 0.80 NPC1 (0.37) PNMTNPC1RAB9A
SCHEMBL7716230 0.80 PNMT (0.34) PNMTNPC1RAB9A
Hydrochloric Acid SCHEMBL7076115 0.79 PNMT (0.32) PNMTNPC1RAB9A
SCHEMBL812024 0.79 PNMT (0.32) PNMTNPC1RAB9A
SCHEMBL6558849 0.79 PNMT (0.32) PNMTNPC1RAB9A
Hydrochloric Acid SCHEMBL6445783 0.77 PNMT (0.31) PNMTNPC1RAB9A
Hydrochloric Acid SCHEMBL812025 0.77 PNMT (0.33) PNMTNPC1RAB9A
SCHEMBL2805385 0.76 PNMT (0.32) PNMT
SCHEMBL814538 0.76 PNMT (0.32) PNMTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6664352-B1 Impregnating porous particulate support in mechanically fluidized state with catalyst material in mixer having horizontal axis counter-rotating interlocking mixing paddles BOREALIS TECHNOLOGY OY (FI) 2003-12-16 US disclosed
US-20030078340-A1 Impregnating a mechanically fluidized porous particulate support material with a catalyst and polymerizing monomer(s) to produce polymer; heating mixture antioxidants, ultraviolet radiation stabilizer, diluent and metal stearate; depositing BOREALIS TECHNOLOGY OY (FI) 2003-04-24 US disclosed
US-5945367-A Metallocenes with silyl-substituted bridges and their use for olefin polymerization BOREALIS AG (AT) 1999-08-31 US disclosed