SCHEMBL2806876

SCHEMBL2806876

C[SiH](C)[Zr](Cl)(Cl)(c1cccc2c1Cc1ccccc1-2)C1C=Cc2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7076113 0.88 PNMT (0.30) PNMTNPC1RAB9A
SCHEMBL2801806 0.83 NPC1 (0.37) PNMTNPC1RAB9A
SCHEMBL7716230 0.82 PNMT (0.34) PNMTNPC1RAB9A
SCHEMBL6558849 0.82 PNMT (0.32) PNMTNPC1RAB9A
SCHEMBL812024 0.82 PNMT (0.32) PNMTNPC1RAB9A
Hydrochloric Acid SCHEMBL812025 0.79 PNMT (0.33) PNMTNPC1RAB9A
SCHEMBL1978363 0.79 PNMT (0.32) PNMTNPC1RAB9A
SCHEMBL2805385 0.79 PNMT (0.32) PNMT
SCHEMBL814538 0.79 PNMT (0.32) PNMTNPC1RAB9A
SCHEMBL8384440 0.78 NPC1 (0.37) PNMTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2050771-B1 FILM OR LAMINATE COMPRISING ETHYLENE RESIN OR ETHYLENE RESIN COMPOSITION MITSUI CHEMICALS INC (JP) 2020-07-15 EP disclosed
US-8785574-B2 Bridged metallocene compound, olefin polymerization catalyst containing the same, and ethylene polymer obtained with the catalyst MITSUI CHEMICALS, INC. (JP) 2014-07-22 US disclosed
US-20140114031-A1 BRIDGED METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST CONTAINING THE SAME, AND ETHYLENE POLYMER OBTAINED WITH THE CATALYST PRIME POLYMER CO., LTD. (JP) 2014-04-24 US disclosed
EP-2218725-B1 BRIDGED METALLOCENE OLEFIN POLYMERIZATION CATALYST AND ETHYLENE POLYMER OBTAINED BY USING THE CATALYST MITSUI CHEMICALS INC (JP) 2013-10-23 EP disclosed
US-8299193-B2 Film or laminate comprising ethylene-based resin or ethylene-based resin composition MITSUI CHEMICALS, INC. (JP) 2012-10-30 US disclosed
US-7858723-B2 Ethylene-based resin and molded object obtained therefrom MITSUI CHEMICALS, INC. (JP) 2010-12-28 US disclosed
US-20100292421-A1 BRIDGED METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST CONTAINING THE SAME, AND ETHYLENE POLYMER OBTAINED WITH THE CATALYST MITSUI CHEMICALS, INC. 2010-11-18 US disclosed
EP-1849805-B1 ETHYLENIC RESIN AND FORMED ARTICLE OBTAINED THEREFROM MITSUI CHEMICALS INC (JP) 2010-11-10 EP disclosed
EP-2218725-A1 BRIDGED METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST USING THE COMPOUND AND ETHYLENE POLYMER OBTAINED BY USING THE CATALYST Mitsui Chemicals, Inc. (JP) 2010-08-18 EP disclosed
US-20090291285-A1 FILM OR LAMINATE COMPRISING ETHYLENE-BASED RESIN OR ETHYLENE-BASED RESIN COMPOSITION MITSUI CHEMICALS, INC. 2009-11-26 US disclosed
EP-2050771-A1 FILM OR LAMINATE COMPRISING ETHYLENE RESIN OR ETHYLENE RESIN COMPOSITION Mitsui Chemicals, Inc. (JP) 2009-04-22 EP disclosed
US-20080090983-A1 Ethylene-Based Resin and Molded Object Obtained Therefrom MITSUI CHEMICALS, INC. (JP) 2008-04-17 US disclosed
EP-1849805-A1 ETHYLENIC RESIN AND FORMED ARTICLE OBTAINED THEREFROM Mitsui Chemicals, Inc. (JP) 2007-10-31 EP disclosed
US-6372681-B1 METALLOCENE OF TRANSITION METAL AND; METAL OXIDE, SULFIDE, PHOSPHIDE, CARBIDE, NITRIDE, AND/OR SELENIDE; ORGANOALKALINE EARTH OR ZINC COMPOUND; AND ORGANOALUMINUM COMPOUND TOSOH CORPORATION (JP) 2002-04-16 US disclosed
EP-0942006-A2 Catalyst for olefin polymer production and process for olefin polymer production employing the catalyst TOSOH CORPORATION (JP) 1999-09-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100292421-A1 BRIDGED METALLOCENE COMPOUND, OLEFIN POLYMERIZATION CATALYST CONTAINING THE SAME, AND ETHYLENE POLYMER OBTAINED WITH THE CATALYST CAD, ENDOD1, CCT7 PNMT 1132/4885NPC1 1729/4885RAB9A 3251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.