Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | FNTA | P49354 | 2/20 | 0.55 |
| ▸ | FNTB | P49356 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.50 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7077474 | 0.84 | KMT2A (0.63) | KMT2AL3MBTL1LMNAMEN1ALDH1A1 | |
| SCHEMBL3061701 | 0.83 | PKM (0.52) | KMT2AL3MBTL1FNTAFNTBMEN1 | |
| SCHEMBL7076468 | 0.83 | KMT2A (0.59) | KMT2AL3MBTL1LMNAMEN1ALDH1A1 | |
| SCHEMBL3049341 | 0.81 | CA1 (0.51) | KMT2AL3MBTL1FNTAFNTBLMNA | |
| SCHEMBL8337431 | 0.81 | CA1 (0.58) | KMT2AL3MBTL1LMNAMEN1ALDH1A1 | |
| SCHEMBL3061681 | 0.78 | CYP19A1 (0.57) | KMT2AL3MBTL1LMNAALDH1A1POLB | |
| SCHEMBL14697013 | 0.77 | HSD17B10 (0.56) | LMNAALDH1A1POLBCA1CA2 | |
| SCHEMBL14477864 | 0.76 | POLB (0.53) | KMT2AL3MBTL1FNTAFNTBLMNA | |
| SCHEMBL17993697 | 0.75 | TSHR (0.54) | KMT2AFNTAFNTBLMNAALDH1A1 | |
| SCHEMBL20435712 | 0.74 | TP53 (0.54) | KMT2AL3MBTL1LMNAMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030022893-A1 | Hydroxamic and carboxylic acid derivatives | BAXTER ANDREW DOUGLAS (GB) | 2003-01-30 | — | — | US | disclosed |
| US-6465468-B1 | SUCH AS N-HYDROXY-2-(4-(4-CHLOROPHENYL)PIPERAZINE-1-SULFONYL)BENZAMIDE; INHIBITORS OF MATRIX METALLOPROTEINASE, ADAM OR ADAMTS ENZYMES; TREATMENT OF DEGENERATIVE DISEASES AND CERTAIN CANCERS | DARWIN DISCOVERY LIMITED (GB) | 2002-10-15 | — | — | US | disclosed |