Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 7/20 | 0.59 |
| ▸ | SRC | P12931 | 5/20 | 0.56 |
| ▸ | FGFR2 | P21802 | 5/20 | 0.56 |
| ▸ | KDR | P35968 | 5/20 | 0.56 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.56 |
| ▸ | FGFR4 | P22455 | 4/20 | 0.56 |
| ▸ | FGFR3 | P22607 | 4/20 | 0.56 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7079332 | 0.79 | FLT3 (0.54) | FLT3SRCFGFR2KDRFGFR1 | |
| SCHEMBL31060426 | 0.77 | FLT3 (1.00) | FLT3FGFR1PDGFRBPDGFRAKDM4E | |
| SCHEMBL370573 | 0.77 | FLT3 (1.00) | FLT3FGFR1PDGFRBPDGFRAKDM4E | |
| Methane SCHEMBL22343918 | 0.75 | FLT3 (0.96) | FLT3FGFR1PDGFRBPDGFRAKDM4E | |
| SCHEMBL6168778 | 0.75 | ALOX15 (0.59) | FLT3FGFR2FGFR1FGFR3PDGFRB | |
| SCHEMBL7090488 | 0.75 | JAK2 (0.53) | KDM4EMAPTHPGDSRD5A2HSD17B10 | |
| SCHEMBL7565245 | 0.74 | MAPK14 (0.65) | FLT3SRCFGFR2KDRFGFR1 | |
| SCHEMBL6171532 | 0.74 | ALOX15 (0.55) | FLT3SRCFGFR2KDRFGFR1 | |
| Indole-2-Carboxylic Acid SCHEMBL7590299 | 0.74 | KDM4E (0.83) | FLT3PDGFRBPDGFRAKDM4EMAPT | |
| SCHEMBL7080355 | 0.74 | MAPT (0.47) | KDM4EMAPTHSD17B10ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073832-A1 | Novel aminophenyl ketone derivatives | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2003-04-17 | — | — | US | disclosed |
| WO-2002083622-A2 | NOVEL AMINOPHENYL KETONE DERIVATIVES | LEO PHARMA A/S (DK) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073832-A1 | Novel aminophenyl ketone derivatives | MAPKAPK2, MAP3K2, MAP3K1 | FLT3 1230/4885SRC 912/4885FGFR2 1627/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.