Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.53 |
| ▸ | TYK2 | P29597 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CASP1 | P29466 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.47 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7183309 | 0.88 | SRD5A2 (0.54) | JAK2TYK2CYP3A4TSHRCA1 | |
| SCHEMBL7035012 | 0.86 | CYP3A4 (0.48) | JAK2TYK2CYP3A4TSHRCA1 | |
| SCHEMBL1149168 | 0.85 | SRD5A2 (0.60) | JAK2TYK2TSHRRECQLCASP1 | |
| SCHEMBL5963546 | 0.85 | MAPK13 (0.58) | JAK2TYK2ALDH1A1HSD17B10ALOX15 | |
| SCHEMBL11630588 | 0.84 | JAK2 (0.51) | JAK2TYK2CYP3A4TSHRCA1 | |
| SCHEMBL99697 | 0.84 | CASP1 (0.63) | JAK2TYK2CYP3A4TSHRCA1 | |
| SCHEMBL2335079 | 0.84 | KMT2A (0.55) | JAK2TYK2CYP3A4TSHRCA1 | |
| SCHEMBL5174662 | 0.84 | RAB9A (0.48) | JAK2TYK2CYP3A4TSHRRECQL | |
| SCHEMBL5172393 | 0.84 | MAPK13 (0.61) | CYP3A4RECQLALDH1A1RORCRORB | |
| SCHEMBL7194395 | 0.83 | HSD17B10 (0.58) | JAK2TYK2CYP3A4TSHRCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9353224-B2 | Poly(imide-amide) copolymer and composition including poly(imide-amide) copolymer | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2016-05-31 | — | — | US | disclosed |
| US-9353224-B2 | Poly(imide-amide) copolymer and composition including poly(imide-amide) copolymer | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2016-05-31 | — | — | US | disclosed |
| US-20150057426-A1 | POLY(IMIDE-AMIDE) COPOLYMER AND COMPOSITION INCLUDING POLY(IMIDE-AMIDE) COPOLYMER | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2015-02-26 | — | — | US | disclosed |
| US-20150057426-A1 | POLY(IMIDE-AMIDE) COPOLYMER AND COMPOSITION INCLUDING POLY(IMIDE-AMIDE) COPOLYMER | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2015-02-26 | — | — | US | disclosed |
| US-20030171422-A1 | New nitromethyl ketones, process for preparing them and compositions containing them | MERCK PATENT GMBH (DE) | 2003-09-11 | — | — | US | disclosed |
| US-6559185-B2 | Nitromethyl ketone compounds having aldose reduction inhibiting properties and methods for their use | MERCK PATENT GMBH (DE) | 2003-05-06 | — | — | US | disclosed |
| US-20030069312-A1 | Antidiabetic agents | LARDY CLAUDE (FR) | 2003-04-10 | — | — | US | disclosed |
| US-20030064235-A1 | Optical members made of polymide resins | MITSUI CHEMICALS, INC. (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1237015-A1 | OPTICAL MEMBERS MADE OF POLYIMIDE RESINS | Mitsui Chemicals, Inc. (JP) | 2002-09-04 | — | — | EP | disclosed |
| US-6043281-A | ALDOSE REDUCTASE INHIBITORS; TREATMENT OR PREVENTION OF COMPLICATIONS OF DIABETES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-03-28 | — | — | US | disclosed |
| EP-0983226-A1 | NEW NITROMETHYL KETONES, PROCESS FOR PREPARING THEM AND COMPOSITIONS CONTAINING THEM | MERCK PATENT GmbH (DE) | 2000-03-08 | — | — | EP | disclosed |
| US-5932765-A | REDUCTASE INHIBITORS | MERCK PATENT GESELLSCHAFT MIT (DE) | 1999-08-03 | — | — | US | disclosed |
| WO-1998052906-A1 | NEW NITROMETHYL KETONES, PROCESS FOR PREPARING THEM AND COMPOSITIONS CONTAINING THEM | MERCK PATENT GMBH (DE) | 1998-11-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030069312-A1 | Antidiabetic agents | SLC5A1, SLC5A2, GPR119 | JAK2 4640/4885TYK2 4845/4885CYP3A4 300/4885 |
| US-20030171422-A1 | New nitromethyl ketones, process for preparing them and compositions containing them | AKR1B1, AKR1A1, AKR1C1 | JAK2 4863/4885TYK2 4504/4885CYP3A4 212/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.