SCHEMBL70763

SCHEMBL70763

Cc1c(C(=O)O)c(C(=O)O)c(C)n1C

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
USP2 O75604 1/20 0.44
KMT2A Q03164 3/20 0.41
MEN1 O00255 2/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
LDHA P00338 1/20 0.40
LDHB P07195 1/20 0.40
ATM Q13315 1/20 0.40
POLB P06746 1/20 0.36
RECQL P46063 1/20 0.36
LMNA P02545 1/20 0.36
NOTUM Q6P988 2/20 0.36
EGFR P00533 1/20 0.35
CYP3A4 P08684 1/20 0.34
ACHE P22303 1/20 0.34
ALDH1A1 P00352 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7477443 0.90 KDM4E (0.61) KDM4EUSP2KMT2AMEN1L3MBTL1
SCHEMBL16731958 0.87 USP2 (0.44) KDM4EUSP2KMT2AMEN1L3MBTL1
SCHEMBL26967907 0.87 KDM4E (0.42) KDM4EUSP2KMT2AMEN1L3MBTL1
SCHEMBL15330828 0.79 VDR (0.47) KDM4EUSP2KMT2AMEN1L3MBTL1
SCHEMBL25529107 0.78 KMT2A (0.40) KDM4EUSP2KMT2AMEN1L3MBTL1
SCHEMBL23127815 0.76 RAB9A (0.37) KDM4EUSP2KMT2AMEN1L3MBTL1
SCHEMBL26967940 0.76 KDM4E (0.39) KDM4EUSP2KMT2AMEN1L3MBTL1
SCHEMBL10865194 0.76 MAPT (0.44) KDM4EUSP2KMT2AMEN1L3MBTL1
SCHEMBL27795736 0.76 USP2 (0.41) KDM4EUSP2KMT2AMEN1L3MBTL1
SCHEMBL26967878 0.75 KDM4E (0.42) KDM4EUSP2KMT2AMEN1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 KDM4E 717/4885USP2 2928/4885KMT2A 1042/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.