SCHEMBL7076304

SCHEMBL7076304

COc1ccccc1N=NC(=NNc1ccccc1)c1ccccc1.Oc1ccccc1N=NC(=NNc1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 6/20 0.46
RAB9A P51151 5/20 0.46
HTT P42858 5/20 0.46
MAPT P10636 5/20 0.46
TDP1 Q9NUW8 4/20 0.46
KDM4E B2RXH2 4/20 0.46
GAA P10253 4/20 0.46
MAPK1 P28482 2/20 0.46
HSP90AA1 P07900 2/20 0.46
NPC1 O15118 6/20 0.44
KMT2A Q03164 6/20 0.42
SMN1; SMN2 Q16637 4/20 0.42
LMNA P02545 2/20 0.42
ALDH1A1 P00352 3/20 0.40
HPGD P15428 1/20 0.40
ALOX12 P18054 1/20 0.40
TP53 P04637 2/20 0.39
MDM2 Q00987 1/20 0.39
MEN1 O00255 4/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3081914 0.94 RAB9A (0.50) L3MBTL1RAB9AHTTMAPTTDP1
SCHEMBL3064891 0.88 L3MBTL1 (0.54) L3MBTL1RAB9AHTTMAPTTDP1
SCHEMBL3068582 0.82 GRIN2D (0.45) L3MBTL1RAB9AHTTMAPTTDP1
SCHEMBL29397127 0.81 RAB9A (0.46) L3MBTL1RAB9AHTTMAPTTDP1
SCHEMBL3067276 0.76 RAB9A (0.59) L3MBTL1RAB9AHTTMAPTTDP1
SCHEMBL3067269 0.76 RAB9A (0.59) L3MBTL1RAB9AHTTMAPTTDP1
SCHEMBL11000115 0.75 KMT2A (0.64) L3MBTL1HTTMAPTTDP1KDM4E
SCHEMBL11000118 0.75 KMT2A (0.64) L3MBTL1HTTMAPTTDP1KDM4E
SCHEMBL13576443 0.75 NQO1 (0.48) L3MBTL1RAB9AHTTMAPTTDP1
SCHEMBL3077676 0.73 RAB9A (0.52) L3MBTL1RAB9AHTTMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed