Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6043116 | 0.90 | REN (0.54) | REN | |
| SCHEMBL6959225 | 0.81 | REN (0.55) | REN | |
| Hydrochloric Acid SCHEMBL7591012 | 0.80 | REN (0.54) | REN | |
| SCHEMBL6960708 | 0.79 | REN (0.50) | RENGPBAR1 | |
| SCHEMBL6043236 | 0.78 | REN (0.42) | RENGPBAR1 | |
| SCHEMBL6042922 | 0.74 | REN (0.59) | REN | |
| SCHEMBL7073808 | 0.74 | GPBAR1 (0.41) | RENGPBAR1 | |
| SCHEMBL27503586 | 0.72 | SLC6A4 (0.33) | — | |
| SCHEMBL6042189 | 0.71 | REN (0.43) | RENGPBAR1 | |
| SCHEMBL7076314 | 0.70 | REN (0.43) | RENGPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |
| EP-0863875-A1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | F. HOFFMANN-LA ROCHE AG (CH) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997009311-A1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | F. HOFFMANN-LA ROCHE AG (CH) | 1997-03-13 | — | — | WO | disclosed |