Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Ether. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL8743889 | 1.00 | ALDH1A1 (0.37) | ALDH1A1 | |
| Ether SCHEMBL4525310 | 0.96 | ALDH1A1 (0.39) | ALDH1A1 | |
| Ether SCHEMBL5486838 | 0.96 | — | — | |
| Ether SCHEMBL27789726 | 0.92 | ALDH1A1 (0.37) | ALDH1A1 | |
| Ether SCHEMBL5871078 | 0.92 | ALDH1A1 (0.37) | ALDH1A1 | |
| Ether SCHEMBL48456 | 0.87 | — | — | |
| Ether SCHEMBL7121150 | 0.87 | — | — | |
| Ether SCHEMBL11670962 | 0.87 | ALDH1A1 (0.44) | ALDH1A1 | |
| Ether SCHEMBL11670969 | 0.87 | — | — | |
| Ether SCHEMBL10434481 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0751952-B1 | DISPLACEMENT CHROMATOGRAPHY OF PROTEINS USING LOW MOLECULAR WEIGHT DISPLACERS | CRAMER STEVEN M (US) | 2003-07-02 | — | — | EP | disclosed |
| US-5478924-A | Purification by ion exchanging with cationic exchanger | CRAMER STEVEN M (US) | 1995-12-26 | — | — | US | disclosed |