Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 9/20 | 0.41 |
| ▸ | BCAT1 | P54687 | 9/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | RET | P07949 | 3/20 | 0.35 |
| ▸ | IDH1 | O75874 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139297 | 0.84 | BCAT2 (0.40) | BCAT2BCAT1IDH1ALDH1A1GRIN1 | |
| SCHEMBL9137783 | 0.72 | BCAT2 (0.35) | BCAT2BCAT1AR | |
| SCHEMBL6494928 | 0.72 | BCAT2 (0.35) | BCAT2BCAT1 | |
| SCHEMBL9139456 | 0.72 | TP53 (0.35) | BCAT2BCAT1 | |
| SCHEMBL7026368 | 0.71 | RET (0.37) | BCAT2BCAT1ARRETIDH1 | |
| SCHEMBL6494272 | 0.69 | BCAT2 (0.38) | BCAT2BCAT1ALDH1A1 | |
| SCHEMBL9128206 | 0.69 | BCAT1 (0.37) | BCAT2BCAT1IDH1GRIN1GRIN2B | |
| SCHEMBL6698531 | 0.69 | BCAT2 (0.44) | BCAT2BCAT1ARRET | |
| SCHEMBL8895733 | 0.67 | CYP11B1 (0.46) | ARALDH1A1TDP1KDM4EHSD17B10 | |
| SCHEMBL9054537 | 0.67 | DHODH (0.41) | BCAT2BCAT1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882027-B1 | SUBSTITUTED 2-ARYL-1,2,4-TRIAZINE-3,5-DI(THI)ONES AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2003-07-02 | — | — | EP | disclosed |
| US-6159903-A | Substituted 2-aryl-1,2,4-triazine-3,5-di(thi)ones as herbicides | BAYER AKTIENGESELLSCHAFT (DE) | 2000-12-12 | — | — | US | disclosed |
| EP-0882027-A1 | SUBSTITUTED 2-ARYL-1,2,4-TRIAZINE-3,5-DI(THI)ONES AS HERBICIDES | BAYER AG (DE) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997030980-A1 | SUBSTITUTED 2-ARYL-1,2,4-TRIAZINE-3,5-DI(THI)ONES AS HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-28 | — | — | WO | disclosed |