SCHEMBL7076707

SCHEMBL7076707

CCc1cc(O)cc(C)c1OCCCNc1ccc(C(F)(F)F)cn1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.47
POLB P06746 2/20 0.47
PRKAB2 O43741 1/20 0.43
PRKAG1 P54619 1/20 0.43
PRKAA2 P54646 1/20 0.43
PRKAA1 Q13131 1/20 0.43
PRKAG3 Q9UGI9 1/20 0.43
PRKAG2 Q9UGJ0 1/20 0.43
PRKAB1 Q9Y478 1/20 0.43
HCAR3 P49019 3/20 0.38
SCN8A Q9UQD0 2/20 0.37
NPC1 O15118 4/20 0.37
RAB9A P51151 4/20 0.37
KMT2A Q03164 4/20 0.36
MEN1 O00255 3/20 0.36
AGTR1 P30556 1/20 0.36
METAP1 P53582 1/20 0.36
MAPT P10636 2/20 0.36
CDK5 Q00535 2/20 0.35
CDK5R1 Q15078 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7075157 0.97 GAA (0.46) GAAPOLBPRKAB2PRKAG1PRKAA2
SCHEMBL7071525 0.94 GAA (0.47) GAAPOLBPRKAB2PRKAG1PRKAA2
SCHEMBL7073303 0.90 GAA (0.46) GAAPOLBPRKAB2PRKAG1PRKAA2
SCHEMBL7073309 0.86 GAA (0.42) GAAPOLBPRKAB2PRKAG1PRKAA2
SCHEMBL8067304 0.85 GAA (0.47) GAAPOLBNPC1RAB9ASMN1; SMN2
SCHEMBL7071524 0.83 GAA (0.42) GAAPOLBPRKAB2PRKAG1PRKAA2
SCHEMBL7977459 0.83 SCN9A (0.47) GAAPOLB
SCHEMBL7076194 0.83 MRGPRX4 (0.45) GAAPOLBSMN1; SMN2
SCHEMBL7072842 0.83 MRGPRX4 (0.47) GAAPOLBSMN1; SMN2
SCHEMBL7079367 0.82 POLB (0.38) GAAPOLBPRKAB2PRKAG1PRKAA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1217933-C Dihalopropene compound, insecticide/acaricide containing the same and intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 2005-09-07 CN disclosed
CN-1654455-A Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL CO (JP) 2005-08-17 CN disclosed
US-6589914-B2 The dihalopropene compounds of the general formula (I) have excellent insecticidal/acaricidal activity, so that they are satisfactorily effective for the control of noxious insects, mites and ticks. SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-08 US disclosed
US-20030073847-A1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2003-04-17 US disclosed
CN-1088061-C Dihalopropene compound, insecticide/acaricide containing the same and intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 2002-07-24 CN disclosed
US-6376428-B1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-23 US disclosed
CN-1318535-A Dihalopropene compound, insecticide/acaricide containing the same and intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 2001-10-24 CN disclosed
US-6268313-B1 CONTROLLING INSECTS, MITES, TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-31 US disclosed
US-6071861-A FOR THE CONTROL OF NOXIOUS INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, INC. (JP) 2000-06-06 US disclosed
EP-0785923-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2000-04-05 EP disclosed
US-5922880-A CONTROLLING INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-13 US disclosed
CN-1169147-A Dihalopropene compound, insecticide/acaricide containing the same and intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 1997-12-31 CN disclosed
EP-0785923-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-07-30 EP disclosed
WO-1996011909-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073847-A1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production DDT, DDC, AADAC GAA 646/4885POLB 4531/4885PRKAB2 3080/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.