SCHEMBL7073309

SCHEMBL7073309

Cc1cc(O)cc(Cl)c1OCCCNc1ccc(C(F)(F)F)cn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.42
POLB P06746 3/20 0.42
METAP1 P53582 1/20 0.41
PRKAB2 O43741 1/20 0.39
PRKAG1 P54619 1/20 0.39
PRKAA2 P54646 1/20 0.39
PRKAA1 Q13131 1/20 0.39
PRKAG3 Q9UGI9 1/20 0.39
PRKAG2 Q9UGJ0 1/20 0.39
PRKAB1 Q9Y478 1/20 0.39
RPS6KA3 P51812 1/20 0.39
CRHR1 P34998 2/20 0.38
SCN8A Q9UQD0 2/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
PPARD Q03181 1/20 0.37
KMT2A Q03164 3/20 0.36
MAPT P10636 2/20 0.36
MEN1 O00255 2/20 0.36
CDK5 Q00535 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7071524 0.97 GAA (0.42) GAAPOLBMETAP1PRKAB2PRKAG1
SCHEMBL7238775 0.92 PRKAB2 (0.43) GAAPOLBMETAP1PRKAB2PRKAG1
SCHEMBL7076123 0.89 PRKAB2 (0.42) GAAPOLBMETAP1PRKAB2PRKAG1
SCHEMBL7076707 0.86 GAA (0.47) GAAPOLBMETAP1PRKAB2PRKAG1
SCHEMBL7979030 0.84 GAA (0.44) GAAPOLBRPS6KA3NPC1RAB9A
SCHEMBL7075157 0.83 GAA (0.46) GAAPOLBMETAP1PRKAB2PRKAG1
SCHEMBL7965794 0.83 DEGS1 (0.47) GAAPOLBRPS6KA3NPC1RAB9A
SCHEMBL7073032 0.83 METAP1 (0.36) GAAPOLBMETAP1PRKAB2PRKAG1
SCHEMBL7977383 0.82 SCN9A (0.48) PPARD
SCHEMBL7072961 0.82 MRGPRX4 (0.43) GAAPOLBRAB9AKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1217933-C Dihalopropene compound, insecticide/acaricide containing the same and intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 2005-09-07 CN disclosed
CN-1654455-A Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL CO (JP) 2005-08-17 CN disclosed
US-6589914-B2 The dihalopropene compounds of the general formula (I) have excellent insecticidal/acaricidal activity, so that they are satisfactorily effective for the control of noxious insects, mites and ticks. SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-08 US disclosed
US-20030073847-A1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2003-04-17 US disclosed
CN-1088061-C Dihalopropene compound, insecticide/acaricide containing the same and intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 2002-07-24 CN disclosed
US-6376428-B1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-23 US disclosed
CN-1318535-A Dihalopropene compound, insecticide/acaricide containing the same and intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 2001-10-24 CN disclosed
US-6268313-B1 CONTROLLING INSECTS, MITES, TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-31 US disclosed
US-6071861-A FOR THE CONTROL OF NOXIOUS INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, INC. (JP) 2000-06-06 US disclosed
EP-0785923-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2000-04-05 EP disclosed
US-5922880-A CONTROLLING INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-13 US disclosed
CN-1169147-A Dihalopropene compound, insecticide/acaricide containing the same and intermediate for production thereof SUMITOMO CHEMICAL CO (JP) 1997-12-31 CN disclosed
EP-0785923-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-07-30 EP disclosed
WO-1996011909-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073847-A1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production DDT, DDC, AADAC GAA 646/4885POLB 4531/4885METAP1 402/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.