Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | EBP | Q15125 | 4/20 | 0.55 |
| ▸ | DHCR7 | Q9UBM7 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16026439 | 0.85 | ALDH1A1 (0.55) | NPSR1ALDH1A1EBPDHCR7MAPT | |
| SCHEMBL9621707 | 0.81 | EBP (0.71) | NPSR1ALDH1A1EBPDHCR7MAPT | |
| SCHEMBL22834209 | 0.80 | NPSR1 (0.69) | NPSR1ALDH1A1EBPDHCR7MAPT | |
| SCHEMBL29483654 | 0.79 | NPSR1 (0.67) | NPSR1ALDH1A1EBPDHCR7MAPT | |
| SCHEMBL17007406 | 0.79 | NPSR1 (0.67) | NPSR1ALDH1A1EBPDHCR7MAPT | |
| SCHEMBL26064876 | 0.78 | ALDH1A1 (0.77) | ALDH1A1KMT2AMEN1GAAEPHX2 | |
| SCHEMBL22032774 | 0.77 | ALDH1A1 (0.62) | NPSR1ALDH1A1EBPDHCR7MAPT | |
| SCHEMBL18711514 | 0.75 | ALDH1A1 (0.71) | NPSR1ALDH1A1EBPDHCR7MAPT | |
| SCHEMBL10042201 | 0.75 | ALDH1A1 (1.00) | ALDH1A1KMT2AL3MBTL1GAA | |
| SCHEMBL24322690 | 0.74 | NPSR1 (0.51) | NPSR1ALDH1A1EBPDHCR7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720528-A | Oxadiazole sulfonamide compound containing pyrazole structure, and preparation method and application thereof | 贵州大学 | 2024-03-19 | — | — | CN | disclosed |
| CN-105873913-A | Therapeutics targeting truncated adenomatous polyposis coli (APC) proteins | 得克萨斯系统大学评议会 | 2016-08-17 | — | — | CN | disclosed |
| EP-1025086-B1 | BENZAMIDINE DERIVATIVES AS FACTOR XA INHIBITORS | MERCK PATENT GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| US-6492368-B1 | Benzamidine derivatives as factor XA inhibitors | MERCK PATENT GMBH (DE) | 2002-12-10 | — | — | US | disclosed |