Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.69 |
| ▸ | MAPT | P10636 | 8/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.62 |
| ▸ | MEN1 | O00255 | 8/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.62 |
| ▸ | TP53 | P04637 | 5/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.62 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.62 |
| ▸ | AR | P10275 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.57 |
| ▸ | CASP1 | P29466 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30566291 | 0.83 | TP53 (0.72) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL1106639 | 0.83 | TP53 (0.72) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL17353581 | 0.83 | MAPT (0.72) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL4650064 | 0.82 | MAPT (1.00) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL7691881 | 0.82 | KDM4E (0.70) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL1627936 | 0.81 | CYP3A4 (0.82) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL15456750 | 0.81 | CYP3A4 (0.82) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL74701 | 0.79 | CYP3A4 (0.74) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL6700894 | 0.79 | KDM4E (0.70) | KDM4EMAPTCYP3A4MEN1KMT2A | |
| SCHEMBL5130608 | 0.79 | MAPT (0.70) | KDM4EMAPTCYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610738-B2 | Treatment of Alzheimer's Disease by combining both acetylcholinesterase inhibitory activity and antioxidant activity (by virtue of their carbamoyl and flavonoid pharmacophores) | BIOGAL PHARMACEUTICAL CO., LTD. (HU) | 2003-08-26 | — | — | US | disclosed |
| EP-1322632-A1 | N-DISUBSTITUTED CARBAMOYLOXY FLAVONES | Biogal Pharmaceutical Co., Ltd (HU) | 2003-07-02 | — | — | EP | disclosed |
| US-20020128494-A1 | N-Disubstituted carbamoyloxy flavones | BIOGAL PHARMACEUTICAL CO., LTD. (HU) | 2002-09-12 | — | — | US | disclosed |
| WO-2002024677-A1 | N-DISUBSTITUTED CARBAMOYLOXY FLAVONES | BIOGAL PHARMACEUTICAL CO., LTD. (HU) | 2002-03-28 | — | — | WO | disclosed |
| WO-2002024676-A1 | N-DISUBSTITUTED CARBAMOYLOXY FLAVONES | TEVA PHARMACEUTICALS INDUSTRIES, LTD. (IL) | 2002-03-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020128494-A1 | N-Disubstituted carbamoyloxy flavones | CBR3, FOS, CBR1 | KDM4E 366/4885MAPT 3319/4885CYP3A4 1040/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.