Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 7/20 | 0.60 |
| ▸ | CES2 | O00748 | 3/20 | 0.55 |
| ▸ | CES1 | P23141 | 3/20 | 0.55 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | DHODH | Q02127 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | HPGDS | O60760 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259315 | 0.94 | CES2 (0.62) | PARP1CES2CES1HCAR1CYP3A4 | |
| SCHEMBL27940624 | 0.91 | HCAR1 (0.59) | PARP1CES2CES1HCAR1CYP3A4 | |
| SCHEMBL16953124 | 0.89 | PARP1 (0.50) | PARP1CES2CES1HCAR1CYP3A4 | |
| Thiourea SCHEMBL28876257 | 0.87 | CES2 (0.54) | PARP1CES2CES1HCAR1CYP3A4 | |
| SCHEMBL21516794 | 0.85 | PARP1 (0.52) | PARP1CES2CES1HCAR1CYP3A4 | |
| SCHEMBL3090976 | 0.85 | PARP1 (0.52) | PARP1CES2CES1HCAR1CYP3A4 | |
| SCHEMBL31196365 | 0.85 | HCAR1 (0.65) | PARP1CES2CES1HCAR1CYP3A4 | |
| SCHEMBL813450 | 0.85 | PARP1 (0.53) | PARP1CYP3A4SMN1; SMN2DHODHTSHR | |
| SCHEMBL12607365 | 0.84 | PARP1 (0.50) | PARP1CES2CES1HCAR1CYP3A4 | |
| SCHEMBL9631667 | 0.84 | PARP1 (0.50) | PARP1CES2CES1HCAR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030181334-A1 | Herbicidal method | BAYER CROPSCIENCE LIMITED (GB) | 2003-09-25 | — | — | US | disclosed |
| WO-2003051119-A1 | NEW HERBICIDAL COMPOUNDS AND METHOD | BAYER CROPSCIENCE LIMITED (GB) | 2003-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030181334-A1 | Herbicidal method | DDT, HAAO, CYP4X1 | PARP1 4345/4885CES2 195/4885CES1 488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.