Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 9/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 2/20 | 0.35 |
| ▸ | TGM2 | P21980 | 2/20 | 0.35 |
| ▸ | TGM1 | P22735 | 2/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5724082 | 1.00 | ENPP2 (0.41) | ENPP2PPARGUSP30HSP90AA1HSP90AB1 | |
| SCHEMBL5723816 | 1.00 | ENPP2 (0.41) | ENPP2PPARGUSP30HSP90AA1HSP90AB1 | |
| SCHEMBL5724214 | 0.97 | ENPP2 (0.43) | ENPP2HSP90AA1HSP90AB1DRD4 | |
| SCHEMBL5724334 | 0.95 | CHRM4 (0.39) | ENPP2 | |
| SCHEMBL5724588 | 0.87 | FAAH (0.40) | ENPP2 | |
| SCHEMBL5723743 | 0.87 | USP30 (0.37) | ENPP2PPARGUSP30HSP90AA1HSP90AB1 | |
| SCHEMBL5723970 | 0.87 | USP30 (0.37) | ENPP2PPARGUSP30HSP90AA1HSP90AB1 | |
| SCHEMBL5723893 | 0.85 | ENPP2 (0.40) | ENPP2HSP90AA1HSP90AB1F13A1TGM2 | |
| SCHEMBL5724078 | 0.85 | ENPP2 (0.40) | ENPP2HSP90AA1HSP90AB1F13A1TGM2 | |
| SCHEMBL5724146 | 0.85 | ENPP2 (0.43) | ENPP2HSP90AA1HSP90AB1F13A1TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1340757-A1 | 1-METHYLCARBAPENEM DERIVATIVES | Sankyo Company, Limited (JP) | 2003-09-03 | — | — | EP | disclosed |