Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6952604 | 0.73 | ALDH1A1 (0.58) | ALDH1A1LTC4SCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6952602 | 0.73 | ALDH1A1 (0.58) | ALDH1A1LTC4SCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6905605 | 0.70 | ALDH1A1 (0.48) | ALDH1A1LTC4SCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL6905601 | 0.70 | ALDH1A1 (0.48) | ALDH1A1LTC4SCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL3359589 | 0.69 | EPHX2 (1.00) | EPHX2ALDH1A1KMT2ARAB9ANPC1 | |
| (+)-Tranylcypromine SCHEMBL9579777 | 0.69 | ALDH1A1 (0.52) | ALDH1A1LTC4SCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL856249 | 0.68 | MAPT (0.64) | ALDH1A1LTC4SCYP1A2CYP2D6CYP2C9 | |
| SCHEMBL7078039 | 0.68 | ALDH1A1 (0.72) | ALDH1A1KMT2ARAB9ANPC1POLB | |
| SCHEMBL3073976 | 0.68 | EPHX2 (1.00) | EPHX2KMT2ANPSR1 | |
| SCHEMBL14571398 | 0.68 | ALDH1A1 (0.58) | ALDH1A1LTC4SCYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030125331-A1 | Cyclohexenyl-ethyl-thiourea compounds and use | PARKER HUGHES INSTITUTE | 2003-07-03 | — | — | US | disclosed |
| US-6469034-B1 | TREATMENT OF HIV INFECTION, INCLUDING MUTANT, DRUG-SENSITIVE, DRUG- RESISTANT, AND MULTI-DRUG RESISTANT STRAINS | PARKER HUGHES INSTITUTE | 2002-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125331-A1 | Cyclohexenyl-ethyl-thiourea compounds and use | TPMT, DNTT, BHMT | EPHX2 1139/4885ALDH1A1 3359/4885LTC4S 1637/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.