Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.46 |
| ▸ | F10 | P00742 | 15/20 | 0.44 |
| ▸ | F2 | P00734 | 11/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7084061 | 0.99 | ROCK2 (0.45) | ROCK2CYP3A4CYP3A5F10F2 | |
| SCHEMBL7081339 | 0.93 | F10 (0.44) | ROCK2CYP3A4CYP3A5F10F2 | |
| SCHEMBL7076661 | 0.92 | F10 (0.43) | ROCK2CYP3A4CYP3A5F10F2 | |
| SCHEMBL7078123 | 0.91 | ROCK2 (0.44) | ROCK2CYP3A4CYP3A5F10F2 | |
| SCHEMBL7082128 | 0.91 | F10 (0.44) | ROCK2CYP3A4CYP3A5F10F2 | |
| SCHEMBL7081931 | 0.81 | F10 (0.62) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7084065 | 0.80 | F10 (0.61) | F10F2PRSS1PRSS2PRSS3 | |
| SCHEMBL6993652 | 0.79 | ROCK2 (0.42) | ROCK2CYP3A4CYP3A5F10F2 | |
| Acetic Acid SCHEMBL7081948 | 0.78 | F10 (0.59) | F10F2PRSS1PRSS2PRSS3 | |
| Acetic Acid SCHEMBL7081014 | 0.77 | F10 (0.59) | F10F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030162814-A1 | N-substituted 1-amino-1,1-dialkylcarboxylic acid derivatives | MERCK PATENT GMBH (DE) | 2003-08-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162814-A1 | N-substituted 1-amino-1,1-dialkylcarboxylic acid derivatives | F5, CCNY, F2 | ROCK2 4129/4885CYP3A4 4280/4885CYP3A5 3736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.