Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 14/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.33 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.33 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7075103 | 0.93 | REN (0.48) | RENGPBAR1 | |
| SCHEMBL7081233 | 0.92 | REN (0.49) | RENSSTR4SSTR5 | |
| SCHEMBL7079143 | 0.91 | REN (0.49) | RENGPBAR1MEN1KMT2A | |
| SCHEMBL7080889 | 0.90 | REN (0.48) | REN | |
| SCHEMBL7081784 | 0.90 | REN (0.39) | REN | |
| SCHEMBL7076960 | 0.87 | REN (0.55) | REN | |
| SCHEMBL7078742 | 0.86 | REN (0.48) | RENGPBAR1 | |
| SCHEMBL7081368 | 0.86 | REN (0.47) | REN | |
| SCHEMBL7081558 | 0.86 | REN (0.48) | RENGPBAR1SSTR4SSTR5 | |
| SCHEMBL7075214 | 0.86 | REN (0.43) | RENMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0863875-B1 | NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY | HOFFMANN LA ROCHE (CH) | 2003-06-04 | — | — | EP | disclosed |