SCHEMBL7080889

SCHEMBL7080889

COCC1CN(OC(=O)OC(C)(C)C)CC(OCc2ccc3ccccc3c2)C1c1ccc(COCCOCc2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
REN P00797 19/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7081233 0.97 REN (0.49) REN
SCHEMBL7081368 0.95 REN (0.47) REN
SCHEMBL7076960 0.95 REN (0.55) REN
SCHEMBL7075316 0.92 REN (0.45) REN
SCHEMBL7075103 0.91 REN (0.48) REN
SCHEMBL7082373 0.91 REN (0.46) REN
SCHEMBL7078262 0.90 REN (0.49) REN
SCHEMBL7081244 0.89 REN (0.44) REN
SCHEMBL7079143 0.88 REN (0.49) REN
SCHEMBL7077508 0.88 REN (0.54) REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0863875-B1 NEW 4-(OXYALKOXYPHENYL)-3-OXY-PIPERIDINES FOR TREATING HEART AND KIDNEY INSUFFICIENCY HOFFMANN LA ROCHE (CH) 2003-06-04 EP disclosed