Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 7/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8906014 | 0.74 | RXRA (0.44) | RXRA | |
| SCHEMBL8906045 | 0.67 | RXRA (0.40) | RXRA | |
| SCHEMBL8905381 | 0.67 | RXRA (0.40) | RXRA | |
| SCHEMBL4711568 | 0.65 | MEN1 (0.35) | RXRA | |
| SCHEMBL7195771 | 0.65 | RARG (0.48) | RXRA | |
| SCHEMBL4588217 | 0.63 | — | — | |
| SCHEMBL4668056 | 0.61 | RXRA (0.52) | RXRA | |
| SCHEMBL11654659 | 0.61 | RXRA (0.37) | RXRA | |
| SCHEMBL11599145 | 0.61 | RXRA (0.42) | RXRA | |
| SCHEMBL9117387 | 0.60 | RARG (0.43) | RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1324970-A2 | RETINOIDS FOR THE TREATMENT OF EMPHYSEMA | F. HOFFMANN-LA ROCHE AG (CH) | 2003-07-09 | — | — | EP | disclosed |
| WO-2002028810-A2 | RETINOIDS FOR THE TREATMENT OF EMPHYSEMA | F. HOFFMANN-LA ROCHE AG (CH) | 2002-04-11 | — | — | WO | disclosed |