Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | DHODH | Q02127 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | HTT | P42858 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8826118 | 0.83 | KDM4E (0.75) | KDM4EALDH1A1HPGDHSD17B10DHODH | |
| SCHEMBL2087895 | 0.82 | HTT (0.57) | KDM4EALDH1A1HPGDHSD17B10HTT | |
| SCHEMBL15635912 | 0.81 | KDM4E (0.62) | KDM4EALDH1A1HPGDHSD17B10DHODH | |
| SCHEMBL6168326 | 0.80 | DHODH (0.58) | KDM4EALDH1A1HPGDHSD17B10DHODH | |
| SCHEMBL9239004 | 0.79 | KDM4E (0.61) | KDM4EALDH1A1HPGDHSD17B10DHODH | |
| SCHEMBL1523166 | 0.79 | KDM4E (0.54) | KDM4EALDH1A1HPGDHSD17B10DHODH | |
| SCHEMBL28099069 | 0.79 | KDM4E (0.50) | KDM4EALDH1A1HPGDHSD17B10DHODH | |
| SCHEMBL4611285 | 0.78 | DHODH (0.60) | KDM4EALDH1A1HPGDHSD17B10DHODH | |
| SCHEMBL15636237 | 0.78 | MAPT (0.73) | KDM4EALDH1A1HPGDHSD17B10DHODH | |
| SCHEMBL24925568 | 0.78 | MAPT (0.49) | KDM4EALDH1A1HPGDHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059356-A2 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2003-07-24 | — | — | WO | claimed |
| WO-2003059356-A2 | NOVEL ANTI-INFECTIVES | SMITHKLINE BEECHAM CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |