Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 3/20 | 0.37 |
| ▸ | SLC6A11 | P48066 | 7/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.32 |
| ▸ | ST6GAL1 | P15907 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30514382 | 0.89 | TYMP (0.42) | TYMPSLC6A11SLC6A1BACE1ST6GAL1 | |
| SCHEMBL6835021 | 0.86 | TYMP (0.39) | TYMPSLC6A11SLC6A1BACE1ST6GAL1 | |
| SCHEMBL7175441 | 0.83 | TYMP (0.38) | TYMPST6GAL1 | |
| SCHEMBL5201335 | 0.78 | TYMP (0.42) | TYMPSLC6A11SLC6A1KMT2AMEN1 | |
| SCHEMBL17223095 | 0.75 | TYMP (0.41) | TYMPSLC6A11SLC6A1 | |
| SCHEMBL31629449 | 0.73 | PDE4D (0.41) | ALDH1A1BACE1ST6GAL1SMN1; SMN2 | |
| SCHEMBL16401939 | 0.72 | TYMP (0.42) | TYMPSLC6A11SLC6A1 | |
| SCHEMBL5930407 | 0.71 | TYMP (0.47) | TYMPSLC6A11SLC6A1ST6GAL1 | |
| SCHEMBL5930409 | 0.71 | TYMP (0.47) | TYMPSLC6A11SLC6A1ST6GAL1 | |
| SCHEMBL5318029 | 0.71 | BACE1 (0.36) | TYMPKMT2AALDH1A1BACE1ST6GAL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059926-A2 | METHODS AND COMPOSITIONS FOR AMINOACYL-tRNA SYNTHESIS | UNIVERSITY OF MASSACHUSETTS (US) | 2003-07-24 | — | — | WO | disclosed |