SCHEMBL7175441

SCHEMBL7175441

CCOC(=O)CO[C@@H]1[C@H](O)[C@@H](COC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)O[C@@]1(C(=O)c1ccccc1)n1ccc(N)nc1=O

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TYMP P19971 3/20 0.38
ST6GAL1 P15907 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30514382 0.89 TYMP (0.42) TYMPST6GAL1
SCHEMBL6835021 0.89 TYMP (0.39) TYMPST6GAL1
SCHEMBL7079295 0.83 TYMP (0.37) TYMPST6GAL1
SCHEMBL5201335 0.77 TYMP (0.42) TYMPST6GAL1
SCHEMBL17223095 0.77 TYMP (0.41) TYMP
SCHEMBL31629449 0.73 PDE4D (0.41) ST6GAL1
Benzaldehyde SCHEMBL7181882 0.73 TYMP (0.44) TYMPST6GAL1
SCHEMBL8042942 0.73 ST6GAL1 (0.34) TYMPST6GAL1
SCHEMBL5318029 0.73 BACE1 (0.36) TYMPST6GAL1
SCHEMBL16401939 0.72 TYMP (0.42) TYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030036649-A1 2' modified oligonucleotides ISIS PHARMACEUTICALS, INC. 2003-02-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030036649-A1 2' modified oligonucleotides DCLRE1B, POLRMT, POLM TYMP 10/4885ST6GAL1 1797/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.