Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 6/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.44 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5104515 | 0.89 | AVPR2 (0.46) | AVPR2AVPR1AOXTRBRD4ALDH1A1 | |
| SCHEMBL4138728 | 0.75 | HSD17B3 (0.48) | AVPR2AVPR1AHSD17B3ALDH1A1PDK1 | |
| SCHEMBL4138774 | 0.70 | AVPR2 (0.61) | AVPR2AVPR1AOXTR | |
| SCHEMBL4137666 | 0.70 | AVPR2 (0.61) | AVPR2AVPR1AHSD17B3ALDH1A1P2RX7 | |
| SCHEMBL13602473 | 0.66 | DHODH (0.53) | HSD17B3CHEK1DHODHPDK2 | |
| SCHEMBL14758325 | 0.65 | LMNA (0.58) | BRD4ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL31284096 | 0.63 | TUBB4A (0.70) | BRD4ALDH1A1CHEK1 | |
| SCHEMBL4146709 | 0.62 | AVPR2 (0.49) | AVPR2AVPR1AOXTR | |
| SCHEMBL13689895 | 0.62 | DHODH (0.47) | HSD17B3CHEK1DHODHPDK2 | |
| SCHEMBL31284255 | 0.61 | TUBB4A (0.67) | BRD4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030018024-A1 | Biphenyl vasopressin agonists | WYETH | 2003-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030018024-A1 | Biphenyl vasopressin agonists | AVPR2, AVPR1B, AVPR1A | AVPR2 1/4885AVPR1A 3/4885HSD17B3 356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.