SCHEMBL7079429

SCHEMBL7079429

NC(=O)C(SCc1ccccc1)(SCc1ccccc1)C(N)=O

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
PRMT1 Q99873 1/20 0.48
IDO1 P14902 5/20 0.48
NOS1 P29475 2/20 0.48
NOS3 P29474 1/20 0.48
NOS2 P35228 1/20 0.48
CYP2C19 P33261 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.42
HIF1A Q16665 1/20 0.42
PLA2G10 O15496 1/20 0.41
PLA2G2A P14555 1/20 0.41
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
AKR1B1 P15121 1/20 0.40
GAA P10253 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
MAPT P10636 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4956073 0.77 CYP1A2 (0.50) CYP1A2CYP3A4CYP2D6PRMT1IDO1
SCHEMBL11208326 0.76 CYP1A2 (0.44) CYP1A2CYP3A4CYP2D6PRMT1IDO1
SCHEMBL5193497 0.74 CYP3A4 (0.61) CYP1A2CYP3A4CYP2D6PRMT1IDO1
SCHEMBL11205829 0.74 MMP8 (0.49) SMN1; SMN2GAAMAPTKMT2AEPHX1
Dibenzyl Disulfide SCHEMBL28006296 0.74 IDO1 (0.56) IDO1NOS1NOS3NOS2CYP2C19
Carbamic Acid SCHEMBL28267319 0.74 CYP2C19 (0.61) IDO1NOS1NOS3NOS2CYP2C19
Dibenzyl Disulfide SCHEMBL27966611 0.74 IDO1 (0.56) IDO1NOS1NOS3NOS2CYP2C19
Urea SCHEMBL27623582 0.74 CYP2C19 (0.61) IDO1NOS1NOS3NOS2CYP2C19
Dibenzyl Disulfide SCHEMBL27853226 0.72 IDO1 (0.54) IDO1NOS1NOS3NOS2CYP2C19
SCHEMBL1397310 0.72 IDO1 (0.65) IDO1NOS1NOS3NOS2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed