Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5059081 | 0.91 | MAPT (0.55) | SMN1; SMN2ALDH1A1GAAMAPTCYP19A1 | |
| SCHEMBL28013721 | 0.86 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1GAATDP1TSHR | |
| SCHEMBL5086187 | 0.85 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1GAATDP1MAPT | |
| SCHEMBL2491603 | 0.84 | CA12 (0.61) | SMN1; SMN2ALDH1A1TDP1MAPTTSHR | |
| SCHEMBL6718454 | 0.84 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1TDP1MAPTTSHR | |
| SCHEMBL11812375 | 0.83 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1GAATDP1MAPT | |
| SCHEMBL21065593 | 0.83 | LMNA (0.46) | SMN1; SMN2ALDH1A1GAAMAPTCYP1A2 | |
| SCHEMBL9578813 | 0.83 | ALDH1A1 (0.71) | SMN1; SMN2ALDH1A1GAATDP1MAPT | |
| SCHEMBL9141441 | 0.82 | MAPT (0.54) | SMN1; SMN2ALDH1A1GAATDP1MAPT | |
| SCHEMBL5626568 | 0.82 | LMNA (0.62) | SMN1; SMN2ALDH1A1GAAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117280252-A | Multifocal diffractive silicone hydrogel contact lenses | 爱尔康公司 | 2023-12-22 | — | — | CN | claimed |
| CN-115298573-A | High refractive index silicone insert materials for embedded contact lenses | 爱尔康公司 | 2022-11-04 | — | — | CN | claimed |
| CN-106999629-B | Low water content acrylate-acrylamide copolymers for ophthalmic devices | 诺华股份有限公司 | 2020-02-21 | — | — | CN | claimed |
| CN-117280252-A | Multifocal diffractive silicone hydrogel contact lenses | 爱尔康公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-116888193-A | Polysiloxane vinyl cross-linking agent with high refractive index | 爱尔康公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-115698776-A | Insert material with high oxygen permeability coefficient and high refractive index | 爱尔康公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-111712523-B | Ophthalmic product composition | 爱尔兰眼力健公司 | 2023-01-03 | — | — | CN | disclosed |
| CN-115298573-A | High refractive index silicone insert materials for embedded contact lenses | 爱尔康公司 | 2022-11-04 | — | — | CN | disclosed |
| CN-115298574-A | Embedded silicone hydrogel contact lenses | 爱尔康公司 | 2022-11-04 | — | — | CN | disclosed |
| WO-2021121276-A1 | FUSED TETRACYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR, AND MEDICAL USE THEREOF | 江苏恒瑞医药股份有限公司 | 2021-06-24 | — | — | WO | disclosed |
| EP-3728339-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2020-10-28 | — | — | EP | disclosed |
| CN-111712523-A | Ophthalmic product composition | 默克专利股份有限公司 | 2020-09-25 | — | — | CN | disclosed |
| CN-106999629-B | Low water content acrylate-acrylamide copolymers for ophthalmic devices | 诺华股份有限公司 | 2020-02-21 | — | — | CN | disclosed |
| EP-3502147-A1 | COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS | Merck Patent GmbH (DE) | 2019-06-26 | — | — | EP | disclosed |
| US-20030151825-A1 | Polyacrylate-based light adjustable optical element | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2003-08-14 | — | — | US | disclosed |
| WO-2003060565-A2 | POLYACRYLATE BASED LIGHT ADJUSTABLE OPTICAL ELEMENT | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2003-07-24 | — | — | WO | disclosed |
| US-5451607-A | APPLYING HYDRAZONE DERIVATIVE TO A LOCUS TO CONTROL PESTS | SUMITOMO CHEMICAL CO., LTD. (JP) | 1995-09-19 | — | — | US | disclosed |
| CN-1078460-A | The method for making of hydrazone derivative and application | SUMITOMO CHEMICAL CO (JP) | 1993-11-17 | — | — | CN | disclosed |
| EP-0567138-A2 | Hydrazone derivatives, process for producing the same, insecticides and/or acaricides containing the same as active ingredient and intermediate compounds thereof | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1993-10-27 | — | — | EP | disclosed |