Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 3/20 | 0.43 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.43 |
| ▸ | APOB | P04114 | 3/20 | 0.42 |
| ▸ | MTTP | P55157 | 3/20 | 0.42 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6788348 | 0.90 | MTTP (0.51) | APOBMTTP | |
| SCHEMBL7084075 | 0.88 | CA12 (0.43) | ITGB1ITGA4APOBMTTPDGAT1 | |
| SCHEMBL7080710 | 0.87 | SORT1 (0.43) | SORT1APOBMTTPRXFP1KIT | |
| SCHEMBL7079735 | 0.86 | SORT1 (0.42) | SORT1ITGB1ITGA4APOBMTTP | |
| SCHEMBL7087226 | 0.85 | SMO (0.49) | SORT1RXFP1KDRMEN1KMT2A | |
| SCHEMBL6488561 | 0.85 | SMO (0.43) | SORT1APOBMTTPKITKDR | |
| SCHEMBL6793979 | 0.84 | MTTP (0.53) | APOBMTTP | |
| SCHEMBL27583427 | 0.84 | PDE2A (0.46) | SORT1ITGB1ITGA4APOBMTTP | |
| SCHEMBL7133280 | 0.80 | SORT1 (0.43) | SORT1ITGB1APOBMTTPCA12 | |
| SCHEMBL7085703 | 0.80 | AOC3 (0.50) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |