Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SORT1 | Q99523 | 4/20 | 0.42 |
| ▸ | MTTP | P55157 | 3/20 | 0.41 |
| ▸ | APOB | P04114 | 2/20 | 0.41 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.38 |
| ▸ | UGCG | Q16739 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7084233 | 0.90 | SORT1 (0.45) | SORT1MTTPAPOBITGB1ITGA4 | |
| SCHEMBL6792606 | 0.90 | MTTP (0.49) | MTTPAPOBSMOUGCG | |
| SCHEMBL6679626 | 0.87 | SORT1 (0.40) | SORT1ITGB1ITGA4MEN1KMT2A | |
| SCHEMBL7079740 | 0.86 | SORT1 (0.43) | SORT1MTTPAPOBITGB1ITGA4 | |
| SCHEMBL6492676 | 0.85 | MTTP (0.41) | SORT1MTTPAPOBSMOKIT | |
| SCHEMBL7080710 | 0.85 | SORT1 (0.43) | SORT1MTTPAPOBRXFP1CA12 | |
| SCHEMBL7133280 | 0.80 | SORT1 (0.43) | SORT1MTTPAPOBITGB1CA12 | |
| SCHEMBL6792150 | 0.80 | MTTP (0.49) | MTTPAPOBSMOUGCG | |
| SCHEMBL7134201 | 0.79 | LRRK2 (0.51) | SORT1KMT2AMAPT | |
| SCHEMBL6493468 | 0.79 | GCGR (0.39) | SORT1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |