SCHEMBL7079762

SCHEMBL7079762

NC(=O)Oc1ccc(NC(=O)c2ccccc2Nc2cccc(C(F)(F)F)c2)cc1

nearest known ligand 0.73

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 19/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28670788 0.87 RXFP1 (0.76) RXFP1
SCHEMBL15528884 0.85 RXFP1 (1.00) RXFP1
SCHEMBL28681534 0.84 RXFP1 (0.83) RXFP1
SCHEMBL28473857 0.82 RXFP1 (0.79) RXFP1
SCHEMBL30112566 0.82 RXFP1 (0.79) RXFP1
SCHEMBL28665402 0.82 RXFP1 (0.80) RXFP1
SCHEMBL15529210 0.81 RXFP1 (1.00) RXFP1
SCHEMBL28689416 0.81 RXFP1 (0.76) RXFP1
SCHEMBL28679796 0.81 RXFP1 (0.76) RXFP1
SCHEMBL9268782 0.79 RXFP1 (0.78) RXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1326835-A1 BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2003-07-16 EP disclosed
WO-2002028835-A1 BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-04-11 WO disclosed