Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.43 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6795713 | 0.90 | CTPS1 (0.49) | CTPS1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6796213 | 0.81 | CTPS1 (0.49) | CTPS1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6794201 | 0.78 | LMNA (0.56) | CTPS1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6796525 | 0.75 | MEN1 (0.49) | CTPS1MEN1KMT2ACYP2D6MAPT | |
| SCHEMBL6670037 | 0.73 | AVPR2 (0.43) | MEN1KMT2AMAPTLMNAKDM4E | |
| SCHEMBL6668952 | 0.72 | LMNA (0.41) | MAPTLMNAHTTKDM4ESMN1; SMN2 | |
| SCHEMBL7087415 | 0.71 | CHRNB2 (0.51) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL7138922 | 0.71 | LMNA (0.61) | CTPS1MEN1KMT2ACYP2D6MAPT | |
| SCHEMBL23140029 | 0.71 | CTPS1 (0.75) | CTPS1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6789887 | 0.69 | LMNA (0.58) | CTPS1MEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1326835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002028835-A1 | BENZAMIDE COMPOUNDS AS APO B SECRETION INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-04-11 | — | — | WO | disclosed |