Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 11/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 8/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | F2 | P00734 | 3/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | F9 | P00740 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080820 | 0.95 | F10 (0.43) | F10RIPK1PRSS1F2PRSS2 | |
| SCHEMBL7076322 | 0.86 | F10 (0.51) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7079506 | 0.81 | F10 (0.50) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7082839 | 0.79 | F10 (0.53) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7083090 | 0.77 | F10 (0.51) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7135037 | 0.77 | F10 (0.48) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7007614 | 0.76 | F10 (0.65) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7006420 | 0.76 | F10 (0.65) | F10PRSS1F2PRSS2PRSS3 | |
| SCHEMBL7081749 | 0.76 | F10 (0.42) | F10PRSS1F2PRSS2PRSS3 | |
| Trifluoroacetic Acid SCHEMBL7080631 | 0.75 | F10 (0.56) | F10PRSS1F2PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322618-A1 | AMINO HETEROCYCLIC COMPOUNDS (FACTOR X A? INHIBITORS 14) | MERCK PATENT GmbH (DE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2002024654-A1 | AMINO HETEROCYCLIC COMPOUNDS (FACTOR XA INHIBITORS 14) | MERCK PATENT GMBH (DE) | 2002-03-28 | — | — | WO | disclosed |