Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | HPGD | P15428 | 2/20 | 0.75 |
| ▸ | THRB | P10828 | 1/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | NPY1R | P25929 | 1/20 | 0.60 |
| ▸ | NPY2R | P49146 | 1/20 | 0.60 |
| ▸ | KIF11 | P52732 | 1/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29952837 | 0.90 | KDM4E (0.61) | KDM4EALDH1A1HPGDTHRBKMT2A | |
| SCHEMBL1586810 | 0.86 | KDM4E (1.00) | KDM4EALDH1A1HPGDTHRBKMT2A | |
| SCHEMBL2816058 | 0.84 | ALDH1A1 (0.67) | KDM4EALDH1A1HPGDTHRBKMT2A | |
| SCHEMBL5962663 | 0.82 | ALDH1A1 (0.60) | KDM4EALDH1A1HPGDTHRBKMT2A | |
| SCHEMBL3095750 | 0.81 | RXFP1 (0.68) | KDM4EALDH1A1HPGDTHRBKMT2A | |
| SCHEMBL3037898 | 0.81 | MAP2 (0.63) | ALDH1A1HPGDTHRBKMT2AMEN1 | |
| SCHEMBL2730323 | 0.81 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDTHRBKMT2A | |
| SCHEMBL8315715 | 0.81 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDTHRBKMT2A | |
| SCHEMBL13983383 | 0.81 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDTHRBKMT2A | |
| SCHEMBL30844878 | 0.81 | KDM4E (0.67) | KDM4EALDH1A1HPGDTHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057212-A1 | POLYAMIDE DERIVATIVES POSSESSING ANTIBACTERIAL, ANTIFUNGAL OR ANTITUMOR ACTIVITY | GENELABS TECHNOLOGIES, INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| WO-2002000650-A9 | NOVEL COMPOUNDS POSSESSING ANTIBACTERIAL, ANTIFUNGAL OR ANTITUMOR ACTIVITY | GENELABS TECH INC (US) | 2003-03-06 | — | — | WO | disclosed |