Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | THRB | P10828 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | NPY1R | P25929 | 1/20 | 0.57 |
| ▸ | NPY2R | P49146 | 1/20 | 0.57 |
| ▸ | KIF11 | P52732 | 2/20 | 0.56 |
| ▸ | GFER | P55789 | 2/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080072 | 0.90 | KDM4E (0.75) | KDM4EALDH1A1HPGDTHRBKMT2A | |
| SCHEMBL14211006 | 0.83 | KDM4E (0.75) | KDM4EALDH1A1HPGDTHRBKMT2A | |
| SCHEMBL2816058 | 0.81 | ALDH1A1 (0.67) | KDM4EALDH1A1HPGDTHRBKMT2A | |
| SCHEMBL8687432 | 0.80 | ALDH1A1 (0.54) | KDM4EALDH1A1HPGDTHRBKMT2A | |
| SCHEMBL30366673 | 0.80 | KIF11 (0.74) | KDM4EALDH1A1HPGDTHRBKMT2A | |
| SCHEMBL2333579 | 0.80 | KIF11 (0.74) | KDM4EALDH1A1HPGDTHRBKMT2A | |
| SCHEMBL31506909 | 0.80 | KIF11 (0.74) | KDM4EALDH1A1HPGDTHRBKMT2A | |
| SCHEMBL5962663 | 0.79 | ALDH1A1 (0.60) | KDM4EALDH1A1HPGDTHRBKMT2A | |
| SCHEMBL5278061 | 0.78 | RAB9A (0.64) | KDM4EALDH1A1HPGDTHRBKMT2A | |
| SCHEMBL5634953 | 0.78 | HTR1D (0.58) | KDM4EALDH1A1HPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |