Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPRC | P08575 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA5A | P35218 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5748776 | 0.85 | PTPRC (0.42) | PTPRCS100A4ALDH1A1TDP1CYP3A4 | |
| SCHEMBL9683795 | 0.81 | TDP1 (0.50) | ALDH1A1TDP1CYP3A4POLBMAPT | |
| SCHEMBL27401907 | 0.80 | HSD17B10 (0.55) | ALDH1A1TDP1MAPTMEN1KMT2A | |
| SCHEMBL2552755 | 0.80 | ALDH1A1 (0.55) | ALDH1A1TDP1CYP3A4POLBMAPT | |
| SCHEMBL4980531 | 0.80 | POLB (0.61) | ALDH1A1TDP1POLBMAPTMEN1 | |
| SCHEMBL532452 | 0.79 | PTPRC (0.46) | PTPRCS100A4ALDH1A1TDP1CYP3A4 | |
| SCHEMBL13043154 | 0.79 | POLB (0.53) | PTPRCS100A4ALDH1A1TDP1CYP3A4 | |
| SCHEMBL30279963 | 0.79 | PTPRC (0.46) | PTPRCS100A4ALDH1A1TDP1CYP3A4 | |
| SCHEMBL4301056 | 0.79 | MEN1 (0.45) | ALDH1A1TDP1POLBMAPTMEN1 | |
| SCHEMBL11097917 | 0.79 | TSHR (0.44) | PTPRCS100A4ALDH1A1TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1013636-B1 | Preparation of allylic aromatic compounds | AMERSHAM HEALTH AS (NO) | 2003-07-09 | — | — | EP | disclosed |
| US-6284894-B1 | AROMATIC AMINE IS REACTED FIRST WITH A NITRITE AND THEN WITH AN ALLYLIC OLEFIN HAVING AN ELIMINATABLE TERMINAL SUBSTITUENT. | NYCOMED IMAGING AS (NO) | 2001-09-04 | — | — | US | disclosed |
| EP-1013636-A1 | Preparation of allylic aromatic compounds | NYCOMED IMAGING AS (NO) | 2000-06-28 | — | — | EP | disclosed |