Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1644916 | 0.90 | CYP3A4 (0.51) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL7755626 | 0.84 | TDP1 (0.52) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| Guanidine SCHEMBL1643693 | 0.84 | GAA (0.50) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| Guanidine SCHEMBL1644457 | 0.82 | GAA (0.47) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL2552755 | 0.81 | ALDH1A1 (0.55) | TDP1ALDH1A1CYP3A4TSHRHTT | |
| SCHEMBL10590043 | 0.81 | POLB (0.51) | TDP1ALDH1A1CYP3A4TSHRGAA | |
| SCHEMBL7080073 | 0.81 | PTPRC (0.41) | TDP1ALDH1A1CYP3A4TSHRPOLB | |
| SCHEMBL4980531 | 0.81 | POLB (0.61) | TDP1ALDH1A1TSHRGAATHRB | |
| SCHEMBL27401907 | 0.81 | HSD17B10 (0.55) | TDP1ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL10889681 | 0.80 | TDP1 (0.55) | TDP1ALDH1A1CYP3A4TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112531-A | Acrylic ester and acrylic amide polymers containing nitrophenyl groups in the side chain | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1992-05-12 | — | — | US | disclosed |
| US-5079321-A | Acrylates and acrylamides containing a nitrophenyl group | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1992-01-07 | — | — | US | disclosed |
| US-4239708-A | P-Phenylene bis[imino(thiocarbonyl)] diphosphoramidic acid esters as anthelmentic agents | AMERICAN CYANAMID COMPANY (US) | 1980-12-16 | — | — | US | disclosed |
| US-4137310-A | LARVICIDES | AMERICAN CYANAMID COMPANY (US) | 1979-01-30 | — | — | US | disclosed |