Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CASP7 | P55210 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL389839 | 0.78 | — | — | |
| SCHEMBL30403656 | 0.77 | — | — | |
| SCHEMBL7080993 | 0.73 | MAPT (0.35) | TSHRALDH1A1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL4484217 | 0.71 | — | — | |
| SCHEMBL15657533 | 0.70 | DPP4 (0.39) | RAB9ANPC1HPGDTSHRDPP4 | |
| SCHEMBL8561714 | 0.69 | ALDH1A1 (0.47) | RAB9ANPC1HPGDTSHRALDH1A1 | |
| SCHEMBL6439988 | 0.69 | ALDH1A1 (0.35) | RAB9ANPC1HPGDTSHRALDH1A1 | |
| SCHEMBL9642021 | 0.68 | LMNA (0.43) | RAB9ANPC1TSHRALDH1A1MAPT | |
| SCHEMBL700807 | 0.67 | — | — | |
| SCHEMBL3295474 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322633-A2 | ARYLOXY ESTER AND ACID COMPOUNDS | Aventis Pharma Deutschland GmbH (DE) | 2003-07-02 | — | — | EP | disclosed |
| WO-2001092251-A2 | ARYLOXY ESTER AND ACID COMPOUNDS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-12-06 | — | — | WO | disclosed |